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As early as 1996, a study entitled Reduced intravenous glutathione in the treatment of early Parkinsons disease found that the progression of PD was reduced, and symptoms improved by 42% after only 30 days of treatment

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evaluated the pharmacodynamics, pharmacokinetics, safety, and tolerability of the single and multiple up-dose oral FPN inhibitor VIT-2763 in healthy volunteers and found that VIT-2763 has a safety profile similar to placebo and is well tolerated, with no serious adverse events and discontinuations due to adverse events