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Description

in a few the T4 doses were adjusted to maintain a similar TSH

Rapamycin, a macrolide immunosuppressant generated by the bacterium Streptomyces hygroscopicus, impedes the transition of T cells from the G1 phase to the S phase of the cell cycle by inhibiting IL-2-mediated signaling pathways, thus exerting anti-inflammatory activity [260, 261]