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We have previously reported the development of a hypotonic, gel-forming eye drop vehicle that provided therapeutic drug delivery to the posterior segment in rabbits and pigs [20]

Int J Clin Biochem Res 7(1):3639 Perreault F, Melegari SP, da Costa CH, Rossetto ALOF, Popovic R, Matias WG (2012) Genotoxic effects of copper oxide nanoparticles in Neuro 2A cell cultures