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J Transl Med (2011) 9:129.10.1186/1479-5876-9-129 72 SaeedRWVarmaSPeng-NemeroffTSherryBBalakhanehDHustonJet alCholinergic stimulation blocks endothelial cell activation and leukocyte recruitment during inflammation

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The risk of developing COPD is particularly high among individuals who start smoking at a young age, as tobacco smoke significantly slows lung development