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11 among partially vaccinated (81% effectiveness)

[DOI] [PMC free article] [PubMed] [Google Scholar] Trevisani FDi Marco FQuattrini GLepori NFloris MValsecchi DGiordano LDellOca ICardellini SCinque A, et al

KA 0.75% cream was inferior to HQ 4% cream and KA 2% cream was inferior to modified Kligman's formula (MKF), and the combination of KA 1% cream and HQ 2% cream was superior to either formulation.[16,60,61] Combination of 4% KA with 5% methimazole did not yield better results.[62] Therefore, the clinical improvement in melasma patients is more with MKF and topical HQ 4% compared with KA, and the combination of KA and HQ provides superior improvement compared to KA alone

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