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For example, higher levels of homocysteine mean that certain proteins important in cardiovascular disease and neurodegenerative diseases can end up with a homocysteine attached or incorporated into them.[ref] The process of post-translational protein modification happens all the time and in a number of different ways, including the addition of other amino acids, sugar molecules, or fatty acids

Taken together, these data show that antibody-mediated PS blockade enhances the anti-tumor efficacy of immune checkpoint inhibition

Moreover, hawthorn pectin is efficiently fermented by gut microbiota, leading to a marked increase in short-chain fatty acid levelsparticularly butyratethereby improving the lipid metabolic microenvironment (68)

doi: 10.1038/nchembio.2079 68 DaiEZhangWCongDKangRWangJTangD