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A recent preclinical study reported that a MUC1-based vaccine, when co-administered with a PD-L1 checkpoint inhibitor, significantly boosted tumor-specific CD8 T cell activation and suppressed tumor growth more effectively than monotherapies [247]

The field is ready to move past proving this is a real condition and to start elucidating the specific relationship of ME/CFS symptoms to neuroinflammation

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There are multiple studies that highlight the various transcriptional and epigenetic factors that regulate SLC7A11 expression, however, further studies are required to understand whether SLC7A11 is also regulated via other mechanisms, especially post translational mechanisms and the existence of key interaction partners, etc