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doi: 10.3390/nano13101680 73

AS1411-induced growth inhibition of glioma cells by up-regulation of p53 and down-regulation of Bcl-2 and Akt1 via nucleolin

By scavenging ROS, NAC suppresses the activation of stress kinases, preserving the phosphorylation status of serine/threonine sites on IRS and promoting normal insulin signal transduction, eventually enhancing glucose uptake and utilization in peripheral tissues (190)