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We observed two transcriptomically variant clusters, which expressed both myogenic markers and either endothelial cell markers like Cd34 , Cdh5 and Pecam1 or monocyte and macrophage markers like Ccr2 and C1qa (Extended Data Fig

Efficacy and safety of upadacitinib for 16-week extended induction and 52-week maintenance therapy in patients with moderately to severely active ulcerative colitis