mitochondrial glutathione depletion Glutathione, a Key Survival Antioxidant Maturation of Cytosolic Iron-Sulfur Proteins

Song K, Duan Q, Ren J, Yi J, Yu H, Che H et al (2022) Targeted metabolomics combined with network pharmacology to reveal the protective role of luteolin in pulmonary arterial hypertension

FIGURE 3 7.1 T lymphocyte T cells develop from precursors of bone marrow pluripotent stem cells, acquire immunocompetence in the thymus, and differentiate into distinct subsets such as helper, cytotoxic, and activated T cell effectors

Similar to this mechanism, protein kinase C can also increase intestinal permeability by phosphorylating the myosin light chain [18]

These findings suggest that DUSP2 prevents autoimmune LN, possibly via its inhibition of STAT3 activation