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doi: 10.1016/S0140-6736(14)60649-8 5 MachicadoJDYadavD

These processes occur when there is an imbalance between lipid oxidation and the antioxidant system, leading to cell rupture and death and eventually ferroptosis ( Enzymatic Lipid Peroxidation Enzymatic lipid peroxidation is mainly mediated by the lipoxygenase (LOX) family, which is a group of haeme-type iron-containing enzymes that catalyse PUFAs, primarily adrenergic acid (Ada) and arachidonic acid (AA)

(2) off-the-shelf components (commercially available, wide mouth, small plastic jar containing 2 mL of isopropanol (rubbing alcohol)

13 The GI mucosa and immune cells also significantly contribute to free radical production, particularly in conditions of increased mucosal defense and inflammation