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Dhurat et al

This distinguishes it from GLP-1 medications, which in some patients have been associated with significant lean mass reduction alongside fat loss

In a 2021 study in obese mice, 5-amino-1MQ administration caused significant body mass reductions in the rodents, who achieved body composition and liver adiposity parameters that were comparable to the lean mice in the control group

Cartilage & Joint Protection Because DSIP is often studied for sleep regulation , it is natural to compare it with melatonin , the most widely used sleep supplement: AOD-9604 demonstrated chondroprotective effects in models of cartilage degradation. May reduce proteoglycan loss and support collagen maintenance