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The controversy in the news right now is not about those approved medications

It activates the GHRH receptor via cAMP/PKA and, per Alba et al., increases GH mRNA and somatotroph proliferation

Shmerling, M.D., senior faculty editor of Harvard Health Publishing, who has researched IV therapy

Some studies suggest that long-term use of growth hormone secretagogues like ipamorelin could potentially: increase the risk of certain diseases reduce life expectancy accelerate the aging process However, its crucial to remember that these studies have limitations and more research is needed to fully understand the long-term effects of ipamorelin in humans