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Patients should be educated about the importance of preventing freezing and should take precautions when transporting the medication, particularly during cold weather

In the colon, xylitol is fermented by gut microbiota and studies with human faecal cultures suggest xylitol might act as a prebiotic, increasing the formation of short-chain fatty acids such as butyrate

44,45 In oesophageal squamous cell carcinoma, miR-455-3p participates in the activation of canonical Wnt signalling by simultaneously targeting and inhibiting multiple negative regulatory factors (e.g., DKK3 and GSK3) of the Wnt/-catenin signalling pathway