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Mitochondrion 68:125137

Short-chain fatty acids are substances produced primarily by anaerobic bacteria in the intestinal tract through the fermentation of undigested carbohydrates, and usually have significant physiological regulatory functions, such as protecting the intestinal mucosal barrier and inhibiting intestinal inflammation ( Accumulating evidence establishes the gut microbiota as a critical regulator in functional constipation pathogenesis ( Artemisia argyi polysaccharide (AAP) has been demonstrated to alleviate intestinal inflammation and gut microbiota dysbiosis in mice, playing a crucial role in maintaining intestinal barrier integrity (Figures 6B, C)

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