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Below is focused detail on top studied candidates, how they act, who is showing the most promise, and a compact summary table of targets and reported effects

That the agency is investing public resources to review a compound whose own advocates withdrew their endorsement underscores the difficulty of the regulatory position these peptides occupy

This results in increased oxidative damage to neurons, impaired neuronal function, and the progression of the disease (Liu et al., 2024)

However, their clinical benefits remain modest and variable, and their use is associated with safety concerns such as amyloid-related imaging abnormalities (ARIA), costly treatment, and invasive administration routes