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Furthermore, individuals with active rheumatoid arthritis may experience alleviation of their condition and a reduction in inflammatory markers due to specific flavonoid compounds or flavonoid-rich extracts, such as silymarin and curcumin, with effects superior to those of DMARDs (130, 178)

Four years ago, over six million cases of IBD were reported globally with a reported increase in age prevalence rate from 79 in a dose dependent manner at 50 m and a complete annulling of NF-B activity at 100 m [128]