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This results in marked reduction in the number of capillaries per muscle fiber and dilatation of the remaining capillaries in an effort to compensate for impaired perfusion

A study published in the Diabetes Care journal demonstrated that glutathione levels were lower in individuals with impaired glucose tolerance and type 2 diabetes .[18] A study published in the Journal of Clinical Endocrinology and Metabolism investigated the effects of glutathione on insulin sensitivity in HIV-infected individuals, who have impaired oxidation of fatty acids