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Dihexa acetate dropped off the FDA's Category 2 restricted list on April 22, 2026, as part of the agency's 12-peptide reclassification action

This led to significantly less Hg in the urine of females at 24 h and significantly more Hg in the liver and blood of females (Hirayama and Yasutake 1986)

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TABLE 2 Age-related diseases and their intersection with the circadian system