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Description

The conserved box-1 motif of cytokine receptors is required for association with Jak kinases

Most patients get better consistency with one nightly injection

Yi X, Abas R, Raja Muhammad Rooshdi RAW, Yan J, Liu C, An J, et al

Although the results are limited due to a very small number of studies and patients, an ongoing phase 2 TOP-CKD trial (NCT04258397) that aims to recruit 200 participants and will be completed by December 2024, will hopefully provide additional evidence of the efficacy of pirfenidone as treatment for kidney fibrosis