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Naturally occurring p53 mutations lead to resistance against senescence-targeting peptide FOXO4-DRI Baar MP, et al

This issue has been vigorously debated because of examples in the literature, where peripheral measures either failed to adequately reflect central pathophysiology or did not serve as reliable biological markers

1 Introduction Acute pancreatitis (AP) is a common condition in the digestive system, characterized by the abnormal activation of pancreatic enzymes that can lead to inflammation in the pancreas and surrounding organs ( Recent studies have highlighted the importance of intracellular organelles, particularly mitochondria, in the progression of AP

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