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Lancet 370(9596):14531457

& Koch, W.J

Starting treatment as soon as possible with FDA-approved medications and potentially changing to retatrutide when it becomes available is a practical approach

IRF5 directly boosted inflammatory cytokines expression, such as IL-12, IL-6, IL-23, and IFN-, while IKK regulated the inflammatory TME through the activation of NF-B (164, 165)