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20 , xxviixxix (1981)

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This requirement is most pronounced within the late G1/S phase of the cycle, where the non-oxidative branch of the PPP synthesizes R-5-P, the precursor for nucleotides adenine and guanine, to aid in DNA synthesis before mitosis and complete cell division can occur (Khedkar et al., Inhibition of PPP in OLs with supra concentration of the G-6-P inhibitor dehydroepiandrosterone (DHEA) compromises NADPH supply and causes significant OL death and decreases in myelin

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