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The results of these randomized, placebo-controlled studies showed that intravenous lipoic acid could improve endothelial function in patients with impaired fasting glucose (64) or impaired glucose tolerance (65)

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FIGURE 6 Instead of applying light and photosensitizers to achieve efficient cancer therapy, SDT employs ultrasound (US) and sonosensitizers to trigger 1 O 2 or OH generation, exerting a crucial role in ablation of tumor tissue that is hard to reach through light irradiation