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It is intriguing to see that cellular metabolism and immune activation are so tightly entangled and that a fine-grained interplay is essential to achieve a correct function, said Karsten Hiller, Ph.D., a co-author of the current study and a professor at the Braunschweig University of Technology

In addition, the expression of HDAC4 is also significantly upregulated, accompanied by a series of pathological damages including tubular lumen dilation, the diminished tubular epithelial cell abundance, and inflammatory cell infiltration in ioversol-induced AKI mice model and HK-2 cells exposed to ioversol

Regarding the role of kimchi in activating Nrf2, flavonoids naturally present in cabbage have been suggested to be a natural Nrf2 modulator for skin protection [36, 38]

It has been the subject of multiple peer-reviewed randomized controlled trials in adult and pediatric human participants, with results published in the Journal of Clinical Endocrinology & Metabolism and Neurobiology of Aging