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Multiple studies suggest that mitochondrial function is intrinsically linked to ultimate sperm quality: a decline in mitochondrial membrane potential and insufficient ATP content directly lead to a sharp reduction in sperm motility and fertilization potential, severely affecting acrosome-related functions (146148)

RNA Interference based approach to down regulate osmoregulators of whitefly ( Bemisia tabaci ): potential technology for the control of whitefly

Furthermore, like most transcription factors, direct targeting of NRF2 itself has been extremely challenging