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In a rat model of transient middle cerebral artery occlusion (tMCAO), midazolam was found to protect neurons in the ischemic environment by inhibiting the release of lactate dehydrogenase (LDH) and regulating the expression of apoptosis-related genes to reduce cytotoxicity and apoptosis [145]

NAC has been elucidated to interact with numerous metabolic pathways including, regulation of the cell cycle and apoptosis, carcinogenesis and tumor progression, mutagenesis, gene expression and signal transduction, immune modulation, cytoskeleton organization and trafficking and mitochondrial functions [4]Huang R, Pan Q, Ma X et al

die Bildung des wichtigen, krpereigenen Antioxidans Glutathion, das aus den Aminosuren Cystein, Glycin und Glutamin (in Form von Glutaminsure) besteht und besonders in belastenden Situationen vermehrt gebildet und gebraucht wird

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