Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Size:5mg 031 Purity (HPLC) >= 95%

031 Purity (HPLC) >= 95% Solubility DMSO

612 SMILES: OC(=O)C1=CC=C(C([O-])=O)C(=C1)C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

Product Name CP-Vbn Synonyms SNAP2-Vbn CAS Number Related CAS Molecular Formula C21H19ClN4O2 Molecular Weight 394

Product Name Mal-Propionyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C86H139N13O25 Molecular Weight 1755

Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Size:5mg 031 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by