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Tshala, Boivin and Bramble

In fact, it has been estimated that 98% of small molecules cannot cross the BBB, and this percentage is even higher for larger molecules and cells (Pandit et al., 2020)

(115) reported that purified blueberry polyphenol extract exhibited higher antioxidant activity in different in vitro assays, whereas the crude blueberry extract demonstrated greater antioxidant effectiveness in in vivo models

CDP choline ( citicoline ) is a building block for neurotransmitters that improve cognitive function as it is the essential intermediate for the synthesis of phosphatidylcholine, a major constituent of the gray matter of brain tissue (30%)