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Rohlke F, Stollman N

Accordingly, we are finalizing a revision to the definition of an opioid use disorder treatment service at 410.67(b) by adding paragraph (x) to account for these type of coordinated care and/or referral services, provided by an OTP to link a beneficiary with community resources to address unmet health-related social needs or the need and interest for harm reduction interventions and recovery support services that significantly limit the ability to diagnose or treat a patient's opioid use disorder. We are also revising 410.67(d)(4)(i) by adding paragraph (G) to specify that for the coordinated care and/or referral services described in paragraph (x) of the definition of OUD treatment service at 410.67(b), an adjustment will be made when each additional 30 minutes of these services are furnished, to the bundled payment

Sigma, 4693159001) on ice for 10 min, then sonicated using a Diagenode BioRuptor Pico (Diagenode, B01060010) for ten cycles (30 s on, 30 s off) at 4 C

Drowsiness or sedation Dry mouth Constipation Dizziness or lightheadedness when standing Sudden discontinuation can cause rebound hypertension, so tapering under medical supervision is essential