l carnitine meta analysis In a meta-analysis of 21 RCTs, L-carnitine supplementation improved several outcomes related to cardiometabolic health in people with type 2 diabetes. However, the certainty of the evidence and the clinical importance of Subgroup analysis by L-carnitine dose.

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J Pineal Res 55(2):138148 Drobnik J, Slotwinska D, Olczak S, Tosik D, Pieniazek A, Matczak K, Koceva-Chyla A, Szczepanowska A (2011) Pharmacological doses of melatonin reduce the glycosaminoglycan level within the infarcted heart scar

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Furthermore, the optimization of ferroptosis inducer delivery through advanced nanomedicine approaches, such as engineered nanocarriers, tumor-targeted exosomes, or BBB-penetrating delivery systems, could significantly enhance therapeutic efficacy while minimizing systemic toxicity and off-target effects