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Aging Cell, 8 (5), 524541

By targeting fat for energy, L-Carnitine supports a leaner physique and powers intense workouts without relying on muscle glycogen preserving glycogen stores for when they're specifically needed during high-intensity efforts, while fat handles the steady-state energy demand.

For instance, conjugating AgNPs with antimicrobial peptides, antibodies, or small molecules can improve specificity and reduce non-specific interactions (Ramrez Saenz et al., 2024)

TET1 expression correlated with sensitivity to drugs targeting the PI3KmTOR pathway, and CRISPR-mediated deletion of TET1 in two independent TNBC cell lines resulted in reduced expression of PI3K pathway genes, upregulation of immune response genes, and substantially reduced cellular proliferation, suggesting the dependence of oncogenic pathways on TET1 overexpression