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(2020) Zinc supplementation affects favorably the frequency of migraine attacks: a double-blind randomized placebo-controlled clinical trial

Subsequently, the mixture was dried and washed with chloroform to remove uncapped free DOPC and then redispersed in chloroform solution that containing DOPC, cholesterol, PEG-2000 PE, and DOPE-RGD under sonicated for 15 min

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Failure to eliminate dysfunctional mitochondria leads to the accumulation of mitochondrial ROS and the release of immunogenic mtDNA, both of which act as DAMPs that activate innate immune pathways, including the NLRP3 inflammasome and type I interferon (IFN-I) signaling