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Aetiology is unclear, but it is thought that the antibodies may block TSH receptors and that this results in the hypothyroidism

In the current study, the single and combined effects of the two flavonoids, curcumin and quercetin, against carrageenan-induced acute inflammation in rats were evaluated with emphasis on the role of oxidative stress, anti-inflammatory enzyme, heme oxygenase-1 (HO-1) and proinflammatory cytokine, tumor necrosis factor-alpha (TNF-alpha)

Proc Natl Acad Sci U S A 114: 82838288

Furthermore, it helps to neutralize toxins that have already entered the liver cells, preventing them from causing further harm