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Microglial depletion with clodronate liposomes increases proinflammatory cytokine levels, induces astrocyte activation, and damages blood vessel integrity

Similar content being viewed by others Introduction While currently available therapies have substantially improved the clinical outcomes of many patients with kidney cancers, these treatments are typically ineffective against highly aggressive SMARCB1-deficient kidney malignancies such as renal medullary carcinoma (RMC) 1,2,3,4