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koly L-karnitinu: Energetick metabolismus: L-karnitin hraje dleitou roli v penosu mastnch kyselin do mitochondri, kde probh oxidace tuk na energii

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The contribution made to net drug and xenobiotic metabolism is not known, but adverse reactions by trimethylaminuria subjects to tyramine and sulfur containing drugs have been mentioned, although most tyramine will be metabolised by monoamine oxidases

Functional studies in mice determined that while both the T158M and R133C mutations create MECP2 proteins with reduced DNA-binding ability, the T158M mutation also leads to protein instability, likely resulting in the unique and more severe phenotype presentation (Brown et al