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Statistical analysis The results are presented as mean SD from at least three independent biological replicates, with all analyses performed using GraphPad Prism 7 (GraphPad Software, USA)

Kanemaru and Ichinose, 2025)

The relationship between the AGE-RAGE system and infertility was also documented: AGEs have a negative effects on the reproductive outcome in women undergoing ART (assisted reproduction technology), AGE high levels in NON PCOS women appear to be related to the decrease in ovarian reserve and abnormal folliculogenesis

Methionine : Methionine is an essential amino acid that acts as an antioxidant and supplies sulfur to many molecules in the body