In another example, the unmodified FX polypeptide can be an active FX (FXa) polypeptide having a light chain containing the amino acid sequence shown in residues 1-139 of SEQ ID NO: 134, and a heavy chain containing the amino acid sequence shown as residues 195-448 of SEQ ID NO: 134, or an amino acid sequence having at least 75% sequence identity with the FXa polypeptide having a light chain containing the amino acid sequence shown as residues 1-139 of SEQ ID NO: 134, and a heavy chain containing the amino acid sequence shown as residues 195-448 of SEQ ID NO: 134 In a further example, the unmodified FXa polypeptide is a catalytically active form of the active FXa described above
Abstract Introduction: Repeated hepatic arterial delivery of therapeutic agents to the liver by percutaneously implanted port-catheter systems has been widely used to treat unresectable liver cancer
Disruptions can affect everything from cellular repair to neurotransmitter balance
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