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The reason for this is probably quite apparent when you look at the most common sources of B12 in the diet: meat, fish, and dairy

doi: 10.1016/j.jcis.2016.11.014

Under the action of the six-transmembrane epithelial antigen of prostate 3 (STEAP3), it is reduced to ferrous ion (Fe 2+ ), and with the help of divalent metal transporter 1 (DMT1), Fe 2+ is then released into the cytoplasmic unstable iron pool [19]

First, the hypothalamus in the brain produces a thyrotropin-releasing hormone (TRH), which activates the anterior pituitary gland, found in the brain, to create and secrete thyroid-stimulating hormone (TSH)