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Therapeutic effects of traditional Chinese medicine on gouty nephropathy: Based on Nf-K b signalingpathways

A pro-drug according to the invention includes at least one ester moiety such as an alkyl ester or an aryl ester, e.g., methyl ester, ethyl ester, hydroxyethyl ester, t-butyl ester, cholesteryl ester, isopropyl ester and glyceryl ester

During AD pathogenesis, the EC is one of the first regions to develop tauopathy, which eventually develops in the hippocampus and other cortical regions as the disease progresses 76