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The SLC16 gene family structure, role and regulation in health and disease

10.1093/sleep/33.8.1061 22 BRISA (2022)

showed that MCF-7 breast cancer cells constitutively overexpressing CPT1C displayed an increased FAO-dependent ATP production, and resistance to glucose deprivation or hypoxia 43

In chronic renal failure patients on dialysis, due to reduced dietary intake, limited endogenous synthesis, and clearance by hemodialysis, plasma free carnitine concentration can drop by 70%