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Cancer patients might take Vitamin B12 supplements to deal with deficiencies caused by chemotherapy

2006 Nov;12(9):881-5

Serum B12 levels may therefore serve as a marker of hepatic injury, with higher levels sometimes correlating with disease severity

However, calling it the active-B12 test is slightly misleading, because it measures all B12 bound to transcobalaminincluding biologically inactive forms