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The over-expression of HULC contributes to the malignant development of hepatocellular carcinoma by supporting abnormal lipid metabolism via activation of the acyl-CoA synthetase subunit ACSL1

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Consistent with this evidence, our immunohistochemical and molecular findings reported both a significant reduction in GAD67 enzyme expression and neuronal distribution, along with a striking reduction and altered morphology of PV+ INs in SMA SM CRTX mice