Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG4)-PNP Size:100mg Product Name Pomalidomide-C3-amine HCl Synonyms

Product Name Pomalidomide-C3-amine HCl Synonyms Pomalidomide-4'-C3-amine HCl CAS Number 2154342-45-5 Related CAS 2093388-20-4 (free base) Molecular Formula C16H19ClN4O4 Molecular Weight 366

Product Name 5-(Methoxy-d3)-2-methylaniline Synonyms CAS Number n/a Related CAS Molecular Formula C8H11NO Molecular Weight 140

616 Purity (HPLC) >= 95% Solubility DMSO

CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCN)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG4)-PNP Size:100mg Product Name Pomalidomide-C3-amine HCl SynonymsSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating