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Neoadjuvant immunotherapy for non-small cell lung cancer: right drugs, right patient, right time

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Inhibition of PHGDH with 6-AN markedly reduced the enrichment of 13 C within CR (Figure 4E and Supplemental Figure 3A), as well as the production of endogenous 12 C-CR (Figure 4E and Supplemental Figure 3A), validating the source of the ribose moiety as a product of the PPP