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A growing body of research suggests low-dose colchicine (generally 0.5 mg per day) may reduce the risk of blood clot-related cardiovascular events such as heart attack and strokeespecially when used in conjunction with other standard cardiovascular medicationsthrough its ability to reduce inflammatory signaling in blood vessels

This serves two purposes: receptor sensitivity maintenance (continuous stimulation can lead to downregulation) and allowing you to assess your baseline before adding another layer of intervention

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