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Description

Whereas previous research has demonstrated the feasibility of using peptides to target nuclear hormone receptors 46,47 , to our knowledge, this is the first single molecule that uses a G-protein-coupled-receptor targeting approach to deliver a small-molecule modulator of an ionotropic receptor

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However, there is a lack of research on the potential compensatory effects of tumor cells when the metabolism of glutamine is blocked, which can impact the effectiveness of therapy [178]