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This resulted in 60% ( n = 21) of patients requiring re-call for further testing in the following 6 months

The mechanism of GLP-1-induced nausea involves central GLP-1R activation in the brainstem, specifically in the area postrema, which is the chemoreceptor trigger zone for vomiting

It replenishes mitochondrial energy in neurons and re-regulates the circadian clock (via SIRT1/CLOCK), normalizing dopamine synthesis in the nucleus accumbens to reduce cravings and withdrawal anxiety

Rarely, allergic reactions such as rash or swelling may occur Contraindications Hypersensitivity to any of the components of Neurobion