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Written by Kerri Lewis, Co-founder | Medically reviewed by Nurse Natalia Ostrowska RGN and INP | The Skin to Love Clinic, St

Pre-clinical vs Clinical Translation Challenges Concentrations that produce robust in-vitro fibroblast responses may not translate predictably to in-vivo or human contexts

DOI: DerSimonian R, Laird N

Also metoprolol reduced the plasma norepinephrine concentration in losartan-treated WKY and SHR ( P = NS compared to metoprolol alone, and P 0.013 compared to losartan alone)