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Introduction Glutathione S -transferases (GSTs) are a family of enzymes that conjugate reduced glutathione (GSH) to target molecules in the phase II detoxification of xenobiotic metabolism ( Here we examined the mechanisms of how GSTM1 regulates astrocyte transcriptional program in response to pro-inflammatory signaling and further addressed the impact of GSTM1 loss-of-function on neurons during acute brain inflammation following a systemic injection of lipopolysaccharides (LPS)

this attachment must, therefore, be a crucial step in the sequences of events by which the introduction of an antigen into an animal leads to antibody formation

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After centrifugation at 500 g for 5 min, the nuclei were resuspended in cold buffer solution N for 5 min